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Displaying record number 1599

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MAb ID	polyclonal
HXB2 Location	HIV-1	HIV-1 Epitope Map
Author Location
Epitope
Ab Type
Neutralizing
Species (Isotype)
Patient
Immunogen
Keywords	antibody binding site, assay or method development, escape, mutation acquisition, neutralization, vaccine antigen design

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This review discusses different mechanisms of Ab mediated neutralization and different mechanisms of NAb viral escape and immune evasion. Furthermore, recent research on the protective role of NAbs in HIV-1 infection, as well as preliminary vaccines and immunogens are summarized. Detection of NAbs by neutralization assays and the importance and requirements of assay standardization are highlighted. Humbert2006 (antibody binding site, assay or method development, mutation acquisition, neutralization, vaccine antigen design, escape)

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Humbert2006 Michael Humbert and Ursula Dietrich. The Role of Neutralizing Antibodies in HIV Infection. AIDS Rev., 8(2):51-59, Apr-Jun 2006. PubMed ID: 16848273. Show all entries for this paper.