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Displaying record number 1596

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MAb ID μ5.5 (5.5, mu5.5, Rμ5.5)
HXB2 Location gp160(309-319)
DNA(7149..7181)
gp160 Epitope Map
Author Location gp120( MN)
Epitope IHIGPGRAFYT Epitope Alignment
IHIGPGRAFYT epitope logo
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing L P
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen  
Keywords antibody binding site, binding affinity, neutralization, variant cross-reactivity

Notes

Showing 5 of 5 notes.

References

Showing 5 of 5 references.

Eda2006a Yasuyuki Eda, Mari Takizawa, Toshio Murakami, Hiroaki Maeda, Kazuhiko Kimachi, Hiroshi Yonemura, Satoshi Koyanagi, Kouichi Shiosaki, Hirofumi Higuchi, Keiichi Makizumi, Toshihiro Nakashima, Kiyoshi Osatomi, Sachio Tokiyoshi, Shuzo Matsushita, Naoki Yamamoto, and Mitsuo Honda. Sequential Immunization with V3 Peptides from Primary Human Immunodeficiency Virus Type 1 Produces Cross-Neutralizing Antibodies against Primary Isolates with a Matching Narrow-Neutralization Sequence Motif. J. Virol., 80(11):5552-5562, Jun 2006. PubMed ID: 16699036. Show all entries for this paper.

Maeda1992 Y. Maeda, S. Matsushita, T. Hattori, T. Murakami, and K. Takatsuki. Changes in the Reactivity and Neutralizing Activity of a Type-Specific Neutralizing Monoclonal Antibody Induced by Interaction of Soluble CD4 with gp120. AIDS Res. Hum. Retroviruses, 8:2049-2054, 1992. PubMed ID: 1493053. Show all entries for this paper.

Matsushita2005 Shuzo Matsushita, Soichiro Takahama, Junji Shibata, Tetsuya Kimura, Koichi Shiozaki, Yasuyuki Eda, Atsushi Koito, Toshio Murakami, and Kazuhisa Yoshimura. Ex Vivo Neutralization of HIV-1 Quasi-Species by a Broadly Reactive Humanized Monoclonal Antibody KD-247. Hum. Antibodies, 14(3-4):81-88, 2005. PubMed ID: 16720978. Show all entries for this paper.

Murakami2009 Toshio Murakami, Yasuyuki Eda, Tadashi Nakasone, Yasushi Ami, Kenji Someya, Naoto Yoshino, Masahiko Kaizu, Yasuyuki Izumi, Hajime Matsui, Katsuaki Shinohara, Naoki Yamamoto, and Mitsuo Honda. Postinfection Passive Transfer of KD-247 Protects against Simian/Human Immunodeficiency Virus-Induced CD4+ T-Cell Loss in Macaque Lymphoid Tissue. AIDS, 23(12):1485-1494, 31 Jul 2009. PubMed ID: 19528788. Show all entries for this paper.

Okamoto1998 Y. Okamoto, Y. Eda, A. Ogura, S. Shibata, T. Amagai, Y. Katsura, T. Asano, K. Kimachi, K. Makizumi, and M. Honda. In SCID-hu Mice, Passive Transfer of a Humanized Antibody Prevents Infection and Atrophic Change of Medulla in Human Thymic Implant Due to Intravenous Inoculation of Primary HIV-1 Isolate. J. Immunol., 160:69-76, 1998. PubMed ID: 9551957. Show all entries for this paper.


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