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Displaying record number 1594

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MAb ID C25
HXB2 Location gp160(312-315)
DNA(7158..7169)
gp160 Epitope Map
Author Location ( MOKW)
Research Contact Shuzo Matsushita, Kumamoto University, Japan shuzo@kaiju.medic.kumamoto-u.ac.jp
Epitope GPGR Epitope Alignment
GPGR epitope logo
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P
Species (Isotype) mouse(IgG)
Patient  
Immunogen vaccine
Country Japan
Keywords antibody binding site, antibody generation, antibody sequence, binding affinity, variant cross-reactivity

Vaccine Details

Vaccine type peptide
Vaccine strain B clade, B clade MN, B clade RF, other
Vaccine component Env V3
Adjuvant Complete Freund's Adjuvant (CFA), Incomplete Freund's Adjuvant (IFA)

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Matsushita2005 Shuzo Matsushita, Soichiro Takahama, Junji Shibata, Tetsuya Kimura, Koichi Shiozaki, Yasuyuki Eda, Atsushi Koito, Toshio Murakami, and Kazuhisa Yoshimura. Ex Vivo Neutralization of HIV-1 Quasi-Species by a Broadly Reactive Humanized Monoclonal Antibody KD-247. Hum. Antibodies, 14(3-4):81-88, 2005. PubMed ID: 16720978. Show all entries for this paper.

Eda2006a Yasuyuki Eda, Mari Takizawa, Toshio Murakami, Hiroaki Maeda, Kazuhiko Kimachi, Hiroshi Yonemura, Satoshi Koyanagi, Kouichi Shiosaki, Hirofumi Higuchi, Keiichi Makizumi, Toshihiro Nakashima, Kiyoshi Osatomi, Sachio Tokiyoshi, Shuzo Matsushita, Naoki Yamamoto, and Mitsuo Honda. Sequential Immunization with V3 Peptides from Primary Human Immunodeficiency Virus Type 1 Produces Cross-Neutralizing Antibodies against Primary Isolates with a Matching Narrow-Neutralization Sequence Motif. J. Virol., 80(11):5552-5562, Jun 2006. PubMed ID: 16699036. Show all entries for this paper.


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