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MAb ID	polyclonal
HXB2 Location	HIV-1	HIV-1 Epitope Map
Author Location
Epitope
Subtype	C
Ab Type
Neutralizing	P
Species (Isotype)	human
Patient
Immunogen	HIV-1 infection
Country	India
Keywords	subtype comparisons, variant cross-reactivity

Notes

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Plasma samples collected from HIV-1 infected individuals in India showed extensive cross-neutralizing response against a panel of primary subtype C isolates, suggesting presence of shared neutralization determinants among subtype C in India. Sequence analysis showed limited genetic diversity of Indian subtype C compared to subtype C from Africa. Lakhashe2007 (variant cross-reactivity, subtype comparisons)

References

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Lakhashe2007 Samir K. Lakhashe, Smita S. Kulkarni, Madhuri R. Thakar, Manisha V. Ghate, and Ramesh S. Paranjape. Extensive Cross-Reactive Neutralizing Antibody Response in Indian Patients with Limited Genetic Diversity of HIV-1. Virology, 359(2):295-301, 15 Mar 2007. PubMed ID: 17074379. Show all entries for this paper.