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Displaying record number 142

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MAb ID	HH3
HXB2 Location	Gag(429-444) DNA(2074..2121)	Gag Epitope Map
Author Location	p7(52-67)
Epitope	`RQANFLGKIWPSYKGR`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG2b)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	protein
Vaccine component	p7 Gag

Notes

Showing 2 of 2 notes.

HH3: Binds proximal to the second zinc-finger. Tanchou1995
HH3: Epitopes mapped by ELISA and BIAcore -- does not inhibit NCp7 primer tRNA binding. Tanchou1994

References

Showing 2 of 2 references.

Tanchou1994 V. Tanchou, T. Delaunay, H. de Rocquigny, M. Bodeus, J.-L. Darlix, B. Roques, and R. Benarous. Monoclonal Antibody-Mediated Inhibition of RNA Binding and Annealing Activities of HIV Type 1 Nucleocapsid Protein. AIDS Res. Hum. Retroviruses, 10:983-993, 1994. PubMed ID: 7529035. Show all entries for this paper.

Tanchou1995 V. Tanchou, T. Delaunay, M. Bodeus, B. Roques, J. L. Darlix, and R. Benarous. Conformational Changes between Human Immunodeficiency Virus Type 1 Nucleocapsid Protein NCp7 and its Precursor NCp15 as Detected by Anti-NCp7 Monoclonal Antibodies. J. Gen. Virol., 76:2457-2466, 1995. PubMed ID: 7595349. Show all entries for this paper.