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Displaying record number 141

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MAb ID i5B11
HXB2 Location Gag(382-391)
DNA(1933..1962)
Gag Epitope Map
Author Location p7(5-14)
Epitope NFRNQRKIVK Epitope Alignment
NFRNQRKIVK epitope logo
Ab Type  
Neutralizing  
Species (Isotype) rat(IgG2a)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine component p7 Gag

Notes

Showing 3 of 3 notes.

References

Showing 3 of 3 references.

Otake1994 K. Otake, Y. Fujii, Y. Nishino, Q. Zhong, K. Fujinaga, M. Kameoka, K. Ohki, and K. Ikuta. The Carboxyl-Terminal Region of HIV-1 Nef Protein Is a Cell Surface Domain That Can Interact with CD4+ T Cells. J. Immunol., 153:5826-5837, 1994. This study shows that the C-terminal end of Nef is accessible to Abs. This domain could bind in a soluble form to CD4+, uninfected cells, and this interaction is inhibited in the presence of the C-terminal specific antibodies. Syncytium formation was reduced by these Abs or peptides. Abs could stain IIIB/M10, but not MN/M10, infected cells, in a membrane immunofluorescence assay. PubMed ID: 7989778. Show all entries for this paper.

Tanchou1994 V. Tanchou, T. Delaunay, H. de Rocquigny, M. Bodeus, J.-L. Darlix, B. Roques, and R. Benarous. Monoclonal Antibody-Mediated Inhibition of RNA Binding and Annealing Activities of HIV Type 1 Nucleocapsid Protein. AIDS Res. Hum. Retroviruses, 10:983-993, 1994. PubMed ID: 7529035. Show all entries for this paper.

Tanchou1995 V. Tanchou, T. Delaunay, M. Bodeus, B. Roques, J. L. Darlix, and R. Benarous. Conformational Changes between Human Immunodeficiency Virus Type 1 Nucleocapsid Protein NCp7 and its Precursor NCp15 as Detected by Anti-NCp7 Monoclonal Antibodies. J. Gen. Virol., 76:2457-2466, 1995. PubMed ID: 7595349. Show all entries for this paper.


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