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Displaying record number 1328

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MAb ID	polyclonal
HXB2 Location	gp160(306-322) DNA(7140..7190)	gp160 Epitope Map
Author Location	gp160
Epitope	`RIRPGRAFVTIGK`	Epitope Alignment
Subtype	B
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing
Species (Isotype)	mouse(IgA, IgG)
Patient
Immunogen	vaccine
Keywords	genital and mucosal immunity

Vaccine Details

Vaccine type	influenza
Vaccine strain	B clade IIIB
Vaccine component	Env V3

Notes

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Progesterone-treated BALB/c mice were intravaginally infected with recombinant influenza A virus (Flu/P18IIIB), expressing the immunodominant CTL epitope (P18IIIB, RIRPGRAFVTIGK, H-2Dd). A second immunization administered 2 weeks after the first doubled serum IgG levels and enabled detection of vaginal IgG. Low levels of vaginal IgA were detected in some animals. Garulli2004 (genital and mucosal immunity)

References

Showing 1 of 1 reference.

Garulli2004 Bruno Garulli, Yoshihiro Kawaoka, and Maria R. Castrucci. Mucosal and Systemic Immune Responses to a Human Immunodeficiency Virus Type 1 Epitope Induced upon Vaginal Infection with a Recombinant Influenza A Virus. J. Virol., 78(2):1020-1025, Jan 2004. PubMed ID: 14694134. Show all entries for this paper.