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MAb ID	98-4.9
HXB2 Location	Gag	Gag Epitope Map
Author Location	p24
Epitope
Ab Type
Neutralizing
Species (Isotype)	human(IgG3λ)
Patient
Immunogen	HIV-1 infection
Keywords	antibody generation

Notes

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98-4.9: Antibody generation paper. Antibodies were derived from 58 HIV+ patients. Synthesized by immortalization of peripheral blood cells with Epstein-Barr virus. Gorny1989 (antibody generation)

References

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Isolation Paper
Gorny1989 M. K. Gorny, V. Gianakakos, S. Sharpe, and S. Zolla-Pazner. Generation of human monoclonal antibodies to human immunodeficiency virus. Proc. Natl. Acad. Sci. U.S.A., 86:1624-1628, 1989. This paper described immortalization of B-cells from HIV-1 positive individuals with Epstein-Barr virus, to produce seven stable antibody producing cell lines. PubMed ID: 2922401. Show all entries for this paper.