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Displaying record number 1264

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MAb ID	AG10H9
HXB2 Location	Env	Env Epitope Map
Author Location	gp41(717-751)
Research Contact	BabCO
Epitope
Ab Type
Neutralizing
Species (Isotype)
Patient
Immunogen
Keywords	brain/CSF, variant cross-reactivity

Notes

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AG10H9: Env genes derived from uncultured brain biopsy samples from four HIV-1 infected patients with late-stage AIDS were compared to env genes from PBMC samples. Brain isolates did not differ in the total number or positions of N-glycosylation sites, patterns of coreceptor usage, or ability to be recognized by gp160 and gp41 MAbs. AG10H9 recognized most variants gp41 and gp160 from 3/4 individuals by WB, but not the 4th. Ohagen2003 (brain/CSF, variant cross-reactivity)

References

Showing 1 of 1 reference.

Ohagen2003 Asa Ohagen, Amy Devitt, Kevin J. Kunstman, Paul R. Gorry, Patrick P. Rose, Bette Korber, Joann Taylor, Robert Levy, Robert L. Murphy, Steven M. Wolinsky, and Dana Gabuzda. Genetic and Functional Analysis of Full-Length Human Immunodeficiency Virus Type 1 env Genes Derived from Brain and Blood of Patients with AIDS. J. Virol., 77(22):12336-12345, Nov 2003. PubMed ID: 14581570. Show all entries for this paper.