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Displaying record number 1253

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MAb ID	polyclonal
HXB2 Location	Env	Env Epitope Map
Author Location	Env
Epitope
Subtype	B
Ab Type
Neutralizing
Species (Isotype)	mouse
Patient
Immunogen	vaccine
Keywords	mimotopes, vaccine antigen design

Vaccine Details

Vaccine type	peptide
Adjuvant	QS21

Notes

Showing 1 of 1 note.

Concanavalin A binds to mannose/glucose, and binds to HIV-1. Con A was used to select peptide mimics of carbohydrates that bound to Con A, and the mimetic peptides were then used for BALB/c mouse immunization. Abs raised against the mimetic peptides binds to HIV+ cells, and could weakly neutralize T cell lab adapted strains. Cunto-Amesty2001 (mimotopes, vaccine antigen design)

References

Showing 1 of 1 reference.

Cunto-Amesty2001 Gina Cunto-Amesty, Tarun K. Dam, Ping Luo, Behjatolah Monzavi-Karbassi, C. Fred Brewer, Thomas C. Van Cott, and Thomas Kieber-Emmons. Directing the Immune Response to Carbohydrate Antigens. J. Biol. Chem., 276(32):30490-30498, 10 Aug 2001. PubMed ID: 11384987. Show all entries for this paper.