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Displaying record number 1110

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MAb ID	polyclonal
HXB2 Location	Env	Env Epitope Map
Author Location	(gp120 )
Epitope
Subtype	B
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing	L
Species (Isotype)	mouse(IgA)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	HIV-1 captured on concavalin A-immobilized polystyrene nanospheres, Con A-NS
Vaccine strain	B clade IIIB
Vaccine component	gp120, heat-inactivated virus
Adjuvant	concavalin A-immobilized polystyrene nanospheres

Notes

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Vaginal fluids were collected after intravaginal immunization of BALB/c mice and analyzed for their anti-HIV-1 antibody levels using a IIIB-V3 ELISA and IIIB neutralization assay -- HIV-1 specific IgG was undetectable but anti-HIV IgA antibody response was identified in the vaginal fluids of immunized mice with HIV concavalin A-immobilized polystyrene nanosheres. Kawamura2002

References

Showing 1 of 1 reference.

Kawamura2002 Masaki Kawamura, Taichi Naito, Masamichi Ueno, Takami Akagi, Katsuya Hiraishi, Izumi Takai, Masahiko Makino, Takeshi Serizawa, Kazuhisa Sugimura, Mitsuru Akashi, and Masanori Baba. Induction of Mucosal IgA Following Intravaginal Administration of Inactivated HIV-1-Capturing Nanospheres in Mice. J. Med. Virol., 66(3):291-298, Mar 2002. PubMed ID: 11793379. Show all entries for this paper.