We ask that you read the following before you continue with using the Los Alamos National Laboratory drug resistance mutation database or ADRA, the Antiviral Drug Resistance Analysis tool:
The Los Alamos resistance database, which is the basis for ADRA, was created as a reference for researchers in the field of HIV drug resistance. It is a summary of the drug resistance mutations that have been defined in the literature. ADRA can be used to help researchers rapidly find studies related to a mutation of interest. It was never intended nor is it appropriate for use in clinical decisions about antiretroviral therapy. Only a minority of entries in the table have been clinically validated.
You are advised to use this program to supplement other sources of information, and users should carefully inspect the original citations provided by the links to check that the very basic interpretation shown in the summary table is adequate.
This software is made available on a 'best effort' basis. Although we have made every effort to ensure that the hyperlinks found for any sequence are accurate, their completeness and accuracy will ultimately be defined by the quality of the submitted sequence and will be limited to the studies reviewed in the database.
It is strongly recommended that you take a minute to go over our Sequence Quality Control Tutorial and make sure that your sequences are not contaminated, as this is a very common occurrence in sequencing.
Submitted sequences and results are held on the Los Alamos server for no more than 24 hours after submission and are then automatically deleted. The web connection is NOT secure, however, and it is the user's responsibility to ensure that the submitted sequence does not contain any case numbers, patient details, or other identifiers which could breach confidentiality.