Found 1 matching record:
HXB2 Location | Gag(180-188) | Gag Epitope Map
View variants at this location |
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Epitope |
TPQDLNTML
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Epitope Alignment | ||||
Variants |
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Epitope Name | TL9 | |||||
Species (MHC/HLA) | human |
Showing 1 of 20 variants.
Variant ID. | 916 |
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Epitope Seq. | TPQDLNTML |
Variant Seq. | TPQDLNsML |
Mutations | T/S |
Epitope Location | T7S |
HXB2 Location | T186S |
Mutation Type | E: escape documented in this paper |
Method | CD8 T-cell Elispot - IFNy |
Note | Most common variant for B*4201, B*8101 and B*3910. The variant was less well recognized than the wt, or not recognized at all, by CTLs from B*8101 and B*4201 positive individuals. |
Leslie2006 Alasdair Leslie, David A. Price, Pamela Mkhize, Karen Bishop, Almas Rathod, Cheryl Day, Hayley Crawford, Isobella Honeyborne, Tedi E. Asher, Graz Luzzi, Anne Edwards, Christine M. Rousseau, James I. Mullins, Gareth Tudor-Williams, Vas Novelli, Christian Brander, Daniel C. Douek, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder. Differential Selection Pressure Exerted on HIV by CTL Targeting Identical Epitopes but Restricted by Distinct HLA Alleles from the Same HLA Supertype. J. Immunol., 177(7):4699-4708, 1 Oct 2006. PubMed ID: 16982909. Show all entries for this paper.
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