Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTVATL
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Epitope Alignment | ||||
Variants |
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Epitope Name | SL9 | |||||
Species (MHC/HLA) | human(A2) |
Showing 1 of 6 variants.
Variant ID. | 753 |
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Epitope Seq. | SLYNTVATL |
Variant Seq. | SLfNTiATL |
Mutations | Y/F V/I |
Epitope Location | Y3F V6I |
HXB2 Location | Y79F V82I |
Mutation Type | E: escape documented in this paper |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
Note | Variant was found in the beginning and at the end of a 7 year period in a patient. It was not recognized by patient CTLs. |
Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.
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