Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTVATL
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Epitope Alignment | ||||
Variants |
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Epitope Name | SL9 | |||||
Species (MHC/HLA) | human(A2) |
Showing 1 of 19 variants.
Variant ID. | 481 |
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Epitope Seq. | SLYNTVATL |
Variant Seq. | SLfNaVAvL |
Mutations | Y/F T/A T/V |
Epitope Location | Y3F T5A T8V |
HXB2 Location | Y79F T81A T84V |
Mutation Type | SF: susceptible form |
Note | A minor variant found in one patient. HLA-binding affinity was sufficient to elicit CTL responses. |
Iversen2006 Astrid K. N. Iversen, Guillaume Stewart-Jones, Gerald H. Learn, Natasha Christie, Christina Sylvester-Hviid, Andrew E. Armitage, Rupert Kaul, Tara Beattie, Jean K. Lee, Yanping Li, Pojchong Chotiyarnwong, Tao Dong, Xiaoning Xu, Mark A. Luscher, Kelly MacDonald, Henrik Ullum, Bente Klarlund-Pedersen, Peter Skinhøj, Lars Fugger, Søren Buus, James I. Mullins, E. Yvonne Jones, P. Anton van der Merwe, and Andrew J. McMichael. Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope. Nat. Immunol., 7(2):179-189, Feb 2006. PubMed ID: 16388312. Show all entries for this paper.
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