Found 1 matching record:
HXB2 Location | Gag(263-272) | Gag Epitope Map
View variants at this location |
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Epitope |
KRWIILGLNK
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Epitope Alignment | ||||
Variants |
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Epitope Name | KK10 | |||||
Species (MHC/HLA) | human(B27) |
Showing 1 of 5 variants.
Variant ID. | 392 |
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Epitope Seq. | KRWIILGLNK |
Variant Seq. | KkWIImGLNK |
Mutations | R/K L/M |
Epitope Location | R2K L6M |
HXB2 Location | R264K L268M |
Mutation Type | DHB: diminished HLA binding or increased off-rate |
Method | HLA binding |
Note | Variant bound to B27 poorly compared to the wt. |
Goulder2001c P. J. Goulder, C. Brander, Y. Tang, C. Tremblay, R. A. Colbert, M. M. Addo, E. S. Rosenberg, T. Nguyen, R. Allen, A. Trocha, M. Altfeld, S. He, M. Bunce, R. Funkhouser, S. I. Pelton, S. K. Burchett, K. McIntosh, B. T. Korber, and B. D. Walker. Evolution and transmission of stable CTL escape mutations in HIV infection. Nature, 412(6844):334-8, 19 Jul 2001. PubMed ID: 11460164. Show all entries for this paper.
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