Found 1 matching record:
HXB2 Location | Gag(180-188) | Gag Epitope Map
View variants at this location |
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Epitope |
TPQDLNTML
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Epitope Alignment | ||||
Variants |
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Epitope Name | TL9 | |||||
Species (MHC/HLA) | human(B*39:10, B*81:01) |
Showing 1 of 17 variants.
Variant ID. | 3156 |
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Epitope Seq. | TPQDLNTML{...I...A} |
Variant Seq. | TPsDLNTML{...h...t} |
Mutations | Q/S I/H A/T |
Epitope Location | Q3S I+35H A+60T |
HXB2 Location | Q182S I223H A248T |
Mutation Type | OV: observed variant |
Epitope Subtype | C |
Variant Subtype | C |
Method | Sequence |
Note | A mutation within TL9, Q182S had developed by 32 weeks post-infection , and putative compensatory mutations I223H and A248T had also developed by then in a B*8101-positive subject [Donor HLA = A*2601, A*8001, B*1801, B*8101, Cw*0202, Cw*0401; relatively high VL with CD4+ cell count increasing between years 3-4 post-infection] |
Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.
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