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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 58728

HXB2 Location  Gag(213-227)   Gag Epitope Map
View variants at this location
Epitope DRLHPVHAGPIAPGQ   Epitope Alignment
Variants
DRvHPVHAGPIAPGQ   susceptible form
Epitope Name DQ15
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  3128
Epitope Seq.  DRLHPVHAGPIAPGQ
Variant Seq.  DRvHPVHAGPIAPGQ
Mutations L/V
Epitope Location L3V
HXB2 Location L215V
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Epitope DQ15 was seen to mutate to DRvHPVHAGPIAPGQ in subject CP1 but not in the controller, VC1. Subject CP1 recognizes DRvHPVHAGPIAPGQ as shown by EliSpot.

References

Buckheit2012 Robert W. Buckheit, III, Tracy G. Allen, Angela Alme, Maria Salgado, Karen A. O'Connell, Sarah Huculak, Oluwaseun Falade-Nwulia, Thomas M. Williams, Joel E. Gallant, Robert F. Siliciano, and Joel N. Blankson. Host Factors Dictate Control of Viral Replication in Two HIV-1 Controller/Chronic Progressor Transmission Pairs. Nat Commun, 3:716, 2012. PubMed ID: 22395607. Show all entries for this paper.


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