Found 1 matching record:
HXB2 Location | Gag(74-88) | Gag Epitope Map
View variants at this location |
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Epitope |
ELKSLYNTVATLYCV
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Epitope Alignment | ||||
Variants |
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Epitope Name | Peptide 19 | |||||
Species (MHC/HLA) | human |
Showing 1 of 4 variants.
Variant ID. | 2914 |
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Epitope Seq. | LKSLYNTVATLYCVx |
Variant Seq. | LKSLfNTVATLYCVH |
Mutations | x/H Y/F |
Epitope Location | x15H Y5F |
HXB2 Location | x88H Y78F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | C |
Variant Subtype | A |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | Consensus Clade-A peptide 19, LKSLfNTVATLYCVH, cross reacted to elicit a response from South African subjects carrying clade-C virus. |
Zembe2011 Lycias Zembe, Wendy A. Burgers, Heather B. Jaspan, Linda-Gail Bekker, Helba Bredell, Gwynneth Stevens, Jill Gilmour, Josephine H. Cox, Patricia Fast, Peter Hayes, Eftyhia Vardas, Carolyn Williamson, and Clive M. Gray. Intra- and Inter-Clade Cross-Reactivity by HIV-1 Gag Specific T-Cells Reveals Exclusive and Commonly Targeted Regions: Implications for Current Vaccine Trials. PLoS One, 6(10):e26096, 2011. PubMed ID: 22022524. Show all entries for this paper.
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