Found 1 matching record:
HXB2 Location | Gag(58-72) | Gag Epitope Map
View variants at this location |
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Epitope |
KQIMKQLQPALQTGT
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Epitope Alignment | ||||
Variants |
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Epitope Name | Peptide 15 | |||||
Species (MHC/HLA) | human |
Showing 1 of 4 variants.
Variant ID. | 2910 |
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Epitope Seq. | xKQIMKQLQPALQTGT |
Variant Seq. | cqQImeQLQsALkTse |
Mutations | x/C P/S Q/K G/S T/E K/Q K/E |
Epitope Location | x1C P10S Q13K G15S T16E K2Q K6E |
HXB2 Location | x58C P67S Q70K G72S T73E K59Q K63E |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | C |
Variant Subtype | A |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | Consensus Clade-A peptide 15, cqQImeQLQsALkTse, did not cross react to elicit a response from South African subjects carrying clade-C virus. |
Zembe2011 Lycias Zembe, Wendy A. Burgers, Heather B. Jaspan, Linda-Gail Bekker, Helba Bredell, Gwynneth Stevens, Jill Gilmour, Josephine H. Cox, Patricia Fast, Peter Hayes, Eftyhia Vardas, Carolyn Williamson, and Clive M. Gray. Intra- and Inter-Clade Cross-Reactivity by HIV-1 Gag Specific T-Cells Reveals Exclusive and Commonly Targeted Regions: Implications for Current Vaccine Trials. PLoS One, 6(10):e26096, 2011. PubMed ID: 22022524. Show all entries for this paper.
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