Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTVVTL
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Epitope Alignment | ||||
Variants |
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Epitope Name | SL9 | |||||
Species (MHC/HLA) | human(A*02:01) |
Showing all: 1 variant(s).
Variant ID. | 2690 |
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Epitope Seq. | SLYNTVVTL |
Variant Seq. | SLYNTVaTL |
Mutations | V/A |
Epitope Location | V7A |
HXB2 Location | V83A |
Mutation Type | SF: susceptible form |
Epitope Subtype | B |
Variant Subtype | B |
Method | CD8 T-cell Elispot - IFNy |
Note | SLYNTVVTL underwent adaptation to neo-epitope SLYNTVaTL. 4 subjects had higher EliSpot responses to the neo-epitope than to the non-adapted form. |
Keane2012 Niamh M. Keane, Steven G. Roberts, Coral-Ann M. Almeida, Tanya Krishnan, Abha Chopra, Emma Demaine, Rebecca Laird, Monika Tschochner, Jonathan M. Carlson, Simon Mallal, David Heckerman, Ian James, and Mina John. High-Avidity, High-IFN-gamma-Producing CD8 T-Cell Responses following Immune Selection during HIV-1 Infection. Immunol. Cell Biol., 90(2):224-234, Feb 2012. PubMed ID: 21577229. Show all entries for this paper.
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