Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTVATL
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Epitope Alignment | ||||
Variants |
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Epitope Name | Gag 77 | |||||
Species (MHC/HLA) | human(A2) |
Showing 1 of 6 variants.
Variant ID. | 1661 |
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Epitope Seq. | SLYNTVATL |
Variant Seq. | SLYNTVATi |
Mutations | L/I |
Epitope Location | L9I |
HXB2 Location | L85I |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy, Flow cytometric T-cell cytokine assay, Sequence |
Note | Subject Pt23 carried this variant epitope, and recognized the challenge HXB2 sequence SLYNTVATL. |
Thorn2007 Mette Thorn, Sheila Tang, Dominic Therrien, Henrik Kløverpris, Lasse Vinner, Gitte Kronborg, Jan Gerstoft, Sylvie Corbet, and Anders Fomsgaard. Sequence Conservation of Subdominant HLA-A2-Binding CTL Epitopes in HIV-1 Clinical Isolates and CD8+ T-Lymphocyte Cross-Recognition May Explain the Immune Reaction in Infected Individuals. APMIS, 115(6):757-768, Jun 2007. PubMed ID: 17550385. Show all entries for this paper.
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