Found 1 matching record:
HXB2 Location | Gag(19-27) | Gag Epitope Map
View variants at this location |
||||
---|---|---|---|---|---|---|
Epitope |
IRLRPGGKK
|
Epitope Alignment | ||||
Variants |
|
|||||
Species (MHC/HLA) | human(B27) |
Showing all: 1 variant(s).
Variant ID. | 113 |
---|---|
Epitope Seq. | IRLRPGGKK |
Variant Seq. | IRLRPGGrK |
Mutations | K/R |
Epitope Location | K8R |
HXB2 Location | K26R |
Mutation Type | SF: susceptible form |
Method | Flow cytometric T-cell cytokine assay, Intracellular cytokine staining |
Note | The dominant viral sequence was irlrpggRk, found in 12/15 clones, while the screening sequence IRLRPGGKK was found in 3/15 clones. The least frequent variant stimulated the strongest response. |
Casazza2005a Joseph P. Casazza, Michael R. Betts, Brenna J. Hill, Jason M. Brenchley, David A. Price, Daniel C. Douek, and Richard A. Koup. Immunologic Pressure within Class I-Restricted Cognate Human Immunodeficiency Virus Epitopes during Highly Active Antiretroviral Therapy. J. Virol., 79(6):3653-3663, Mar 2005. PubMed ID: 15731259. Show all entries for this paper.
This is a legacy search page. It is deprecated, will receive no more updates, and will eventually be removed. Please use the new search pages.