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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 54216

HXB2 Location  Gag(240-249)   Gag Epitope Map
View variants at this location
Epitope TSTLQEQIGW   Epitope Alignment
Variants
TtnLQEQIaW   observed variant
Epitope Name TW10
Species (MHC/HLA human(B*57, B*58:01)

Variant Details

Showing 1 of 12 variants.


Variant ID.  1076
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TtnLQEQIaW
Mutations S/T T/N G/A
Epitope Location S2T T3N G9A
HXB2 Location S241T T242N G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note This triple variant was found in 1/80 HLA-B*57/58 subjects infected with Clade B HIV-1, and in no HLA-B*57/5801 negative subjects.

References

Martinez-Picado2006 Javier Martinez-Picado, Julia G. Prado, Elizabeth E. Fry, Katja Pfafferott, Alasdair Leslie, Senica Chetty, Christina Thobakgale, Isobel Honeyborne, Hayley Crawford, Philippa Matthews, Tilly Pillay, Christine Rousseau, James I. Mullins, Christian Brander, Bruce D. Walker, David I. Stuart, Photini Kiepiela, and Philip Goulder. Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1. J. Virol., 80(7):3617-3623, Apr 2006. PubMed ID: 16537629. Show all entries for this paper.


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