Found 1 matching record:
HXB2 Location | Gag(20-29) | Gag Epitope Map
View variants at this location |
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Epitope |
RLRPGGKKKY
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Epitope Alignment | ||||
Variants |
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Epitope Name | RY10 | |||||
Species (MHC/HLA) | human(B62) |
Showing all: 1 variant(s).
Variant ID. | 752 |
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Epitope Seq. | RLRPGGKKKY |
Variant Seq. | RLRPGGrKKY |
Mutations | K/R |
Epitope Location | K7R |
HXB2 Location | K26R |
Mutation Type | SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
Note | Variant was detected over a 5 year time period in a patient. The variant was better recognized than the wt epitope by patient CTLs. |
Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.
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