Found 1 matching record:
HXB2 Location | Gag(162-172) | Gag Epitope Map
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Epitope |
KAFSPEVIPMF
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Epitope Alignment | ||||||||||
Variants |
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Epitope Name | KAF | |||||||||||
Species (MHC/HLA) | human(B57) |
Showing all: 3 variant(s).
Variant ID. | 502 |
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Epitope Seq. | KAFSPEVIPMF |
Variant Seq. | KvFSPEVIPMF |
Mutations | A/V |
Epitope Location | A2V |
HXB2 Location | A163V |
Mutation Type | OV: observed variant |
Note | Variant was found in 2/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs. |
Variant ID. | 503 |
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Epitope Seq. | KAFSPEVIPMF |
Variant Seq. | eAFSPEVIPMF |
Mutations | K/E |
Epitope Location | K1E |
HXB2 Location | K162E |
Mutation Type | OV: observed variant |
Note | Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs. |
Variant ID. | 504 |
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Epitope Seq. | KAFSPEVIPMF |
Variant Seq. | KtFSPEVIPMF |
Mutations | A/T |
Epitope Location | A2T |
HXB2 Location | A163T |
Mutation Type | OV: observed variant |
Note | Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs. |
Jansen2005a Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, and Debbie van Baarle. High Responsiveness of HLA-B57-Restricted Gag-Specific CD8+ T Cells In Vitro May Contribute to the Protective Effect of HLA-B57 in HIV-Infection. Eur. J. Immunol., 35(1):150-158, Jan 2005. PubMed ID: 15593302. Show all entries for this paper.
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