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HIV Molecular Immunology Database

Search the Epitope Variant and Escape Mutation Database

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Found 1 matching record:

Displaying record number 53611

HXB2 Location  Gag(21-35)   Gag Epitope Map
View variants at this location
Epitope LRPGGKKKYRLKHLV   Epitope Alignment
Variants
LRPGGKKKYkLKHLV   observed variant
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  63
Epitope Seq.  LRPGGKKKYRLKHLV
Variant Seq.  LRPGGKKKYkLKHLV
Mutations R/K
Epitope Location R10K
HXB2 Location R30K
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy
Note The sequence contains a known B8 epitope, but the subjects recognizing it were B8-negative. The autologous viral sequence was lrpggkkkyKlkhlv, and the index peptide was recognized.

References

Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.


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