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HIV Molecular Immunology Database

Search the Epitope Variant and Escape Mutation Database

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Found 1 matching record:

Displaying record number 271

HXB2 Location  Gag(263-272)   Gag Epitope Map
View variants at this location
Epitope KRWIILGLNK   Epitope Alignment
Variants
KkWIILGLNK   escape documented in this paper
KRWIImGLNK   observed variant
Species (MHC/HLA human(B*27:05, B27)

Variant Details

Showing all: 2 variant(s).


Variant ID.  371
Epitope Seq.  KRWIILGLNK
Variant Seq.  KkWIILGLNK
Mutations R/K
Epitope Location R2K
HXB2 Location R264K
Mutation Type E: escape documented in this paper
Note Variant is not recognized by CTLs.


Variant ID.  372
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIImGLNK
Mutations L/M
Epitope Location L6M
HXB2 Location L268M
Mutation Type OV: observed variant
Method Sequence
Note Variant observed in 2/32 clade B sequences in the HIV database.

References

Goulder1997d P. J. Goulder, A. Edwards, R. E. Phillips, and A. J. McMichael. Identification of a Novel HLA-B*2705-Restricted Cytotoxic T Lymphocyte Epitope within a Conserved Region of HIV-1 Nef. AIDS, 11:536-538, 1997. PubMed ID: 9084804. Show all entries for this paper.

Goulder1997e P. Goulder, D. Price, M. Nowak, S. Rowland-Jones, R. Phillips, and A. McMichael. Co-Evolution of Human Immunodeficiency Virus and Cytotoxic T-Lymphocyte Responses. Immunol. Rev., 159:17-29, 1997. PubMed ID: 9416500. Show all entries for this paper.


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