Found 5 matching records:
HXB2 Location | Gag(21-35) | Gag Epitope Map
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Epitope |
LRPGGKKKYRLKHLV
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Variants |
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Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 63 |
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Epitope Seq. | LRPGGKKKYRLKHLV |
Variant Seq. | LRPGGKKKYkLKHLV |
Mutations | R/K |
Epitope Location | R10K |
HXB2 Location | R30K |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a known B8 epitope, but the subjects recognizing it were B8-negative. The autologous viral sequence was lrpggkkkyKlkhlv, and the index peptide was recognized. |
Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.
HXB2 Location | Gag(77-91) | Gag Epitope Map
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Epitope |
SLYNTVATLYCVHQR
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Variants |
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Species (MHC/HLA) | human(A*02:01, A*30:02) |
Showing all: 1 variant(s).
Variant ID. | 64 |
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Epitope Seq. | SLYNTVATLYCVHQR |
Variant Seq. | SLfNTVATLYCVHQR |
Mutations | Y/F |
Epitope Location | Y3F |
HXB2 Location | Y79F |
Mutation Type | SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a known A2 epitope and a known A*3002 epitope, and the subjects recognizing it each carry an HLA with a previously-defined restriction. The viral sequence isolated from the subjects was slFntvatlycvhqr, and was reactive. |
Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.
HXB2 Location | Gag(141-155) | Gag Epitope Map
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Epitope |
QMVHQSLSPRTLNAW
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Epitope Alignment | |||||||
Variants |
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Species (MHC/HLA) | human |
Showing all: 2 variant(s).
Variant ID. | 65 |
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Epitope Seq. | QMVHQSLSPRTLNAW |
Variant Seq. | QMtHQnLSPRTLNAW |
Mutations | V/T S/N |
Epitope Location | V3T S6N |
HXB2 Location | V143T S146N |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a known B7/B8 epitope, but the subjects recognizing it are B7- and B8-negative. The viral sequences isolated from the subjects were qmThqNlsprtlnaw and qmvhqAlsprtlnaw, and the index peptide was recognized. |
Variant ID. | 66 |
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Epitope Seq. | QMVHQSLSPRTLNAW |
Variant Seq. | QMVHQaLSPRTLNAW |
Mutations | S/A |
Epitope Location | S6A |
HXB2 Location | S146A |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a known B7/B8 epitope, but the subjects recognizing it are B7- and B8-negative. The viral sequences isolated from the subjects were qmThqNlsprtlnaw and qmvhqAlsprtlnaw, and the index peptide was recognized. |
Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.
HXB2 Location | Gag(293-307) | Gag Epitope Map
View variants at this location |
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Epitope |
FRDYVDRFYKTLRAE
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Epitope Alignment | ||||
Variants |
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Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 67 |
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Epitope Seq. | FRDYVDRFYKTLRAE |
Variant Seq. | FRDYVDRFYKvLRAE |
Mutations | T/V |
Epitope Location | T11V |
HXB2 Location | T303V |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a known epitope (FRDYVDRFYKTL), but the subject recognizing it does not carry HLAs of the previously-defined restriction. The isolated viral sequence was frdyvdrfykVlrae, from the patient that could recognize the peptide. |
Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.
HXB2 Location | Nef(103-117) | Nef Epitope Map
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Epitope |
SKKRQEILDLWVYHT
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Epitope Alignment | ||||
Variants |
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Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 68 |
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Epitope Seq. | SKKRQEILDLWVYHT |
Variant Seq. | SKKRQkILDLWVYHT |
Mutations | E/K |
Epitope Location | E6K |
HXB2 Location | E108K |
Mutation Type | OV: observed variant |
Method | CD8 T-cell Elispot - IFNy |
Note | The sequence contains a previously-defined epitope (KRQEILDLWVY) of unknown HLA restriction. The viral sequence from the subjects that recognized the peptide was skkrqKildlwvyNt. |
Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.
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