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HIV Molecular Immunology Database

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 60988

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HXB2 Location Gag(369-377)
p2p7p1p6(6-14)
DNA(1894..1920)
Gag Epitope Map
Author Location p2p7p1p6(6-14)
Epitope QVTNSATIM Epitope Alignment
QVTNSATIM epitope logo
Subtype B
Species (MHC/HLA) human(B*35:03)
Immunogen HIV-1 infection
Patient MHC/HLA 32645: A*01:01, A*02:01, B*08:01, B*35:03, C*04:01, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 58030

Download this epitope record as JSON.

HXB2 Location Gag(369-377)
p2p7p1p6(6-14)
DNA(1894..1920)
Gag Epitope Map
Author Location Gag
Epitope QVTNSATIM Epitope Alignment
QVTNSATIM epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A*11:01, A*68:01, B*15:18, B*53:01, C*04:01, C*07:04
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


Displaying record number 63149

Download this epitope record as JSON.

HXB2 Location Gag(369-377)
p2p7p1p6(6-14)
DNA(1894..1920)
Gag Epitope Map
Author Location  
Epitope QVTNSATIM Epitope Alignment
QVTNSATIM epitope logo
Epitope Name QM9
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA PR04: A*01:01, A*02, B*08:01, B*35:03, C*04, C*07; PR05: A*03, A*11:01, B*35:03, B*44, C*04, C*05:01
Country Canada
Experimental methods CD8 T-cell Elispot - IFNγ, Proliferation
Keywords characterizing CD8+ T cells, protective allele

Notes

References

Elahi2020 Shokrollah Elahi, Shima Shahbaz, and Stan Houston. Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders Them to an Exhausted Phenotype in HIV-1 Infection. PLoS Pathog., 16(8):e1008696, Aug 2020. PubMed ID: 32760139. Show all entries for this paper.


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