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HIV Molecular Immunology Database

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 53126

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HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location RT Pol(398-407)
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Proliferation
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Plana2004 Montserrat Plana, Felipe Garcia, Annette Oxenius, Gabriel M. Ortiz, Anna Lopez, Anna Cruceta, Gabriel Mestre, Emilio Fumero, Catherine Fagard, Maria Antonia Sambeat, Ferran Segura, José M. Miró, Mireia Arnedo, L. Lopalcos, Tomas Pumarola, Bernard Hirschel, Rodney E. Phillips, Douglas F. Nixon, Teresa Gallart, and Jose M. Gatell. Relevance of HIV-1-Specific CD4+ Helper T-Cell Responses During Structured Treatment Interruptions in Patients With CD4+ T-Cell Nadir Above 400/mm3. J. Acquir. Immune Defic. Syndr., 36(3):791-799, 1 Jul 2004. PubMed ID: 15213562. Show all entries for this paper.


Displaying record number 57409

Download this epitope record as JSON.

HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location Pol(398-407)
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Epitope Name PW10
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection, in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development, chronic infection

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 1379

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HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location RT(410-419)
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Epitope Name PIV
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Oxenius2000b A. Oxenius, D. A. Price, P. J. Easterbrook, C. A. O'Callaghan, A. D. Kelleher, J. A. Whelan, G. Sontag, A. K. Sewell, and R. E. Phillips. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc. Natl. Acad. Sci. U.S.A., 97(7):3382-7, 28 Mar 2000. URL: http://www.pnas.org/cgi/content/full/97/7/3382. PubMed ID: 10737796. Show all entries for this paper.


Displaying record number 52324

Download this epitope record as JSON.

HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location RT
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Epitope Name PIV
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Oxenius2002b Annette Oxenius, Angela R. McLean, Marek Fischer, David A. Price, Sarah J. Dawson, Roland Hafner, Christine Schneider, Helen Joller, Bernard Hirschel, Rodney E. Phillips, Rainer Weber, Huldrych F. Günthard, and Swiss HIV Cohort Study Group. Human Immunodeficiency Virus-Specific CD8+ T-Cell Responses Do Not Predict Viral Growth and Clearance Rates During Structured Intermittent Antiretroviral Therapy. J. Virol., 76(20):10169-10176, Oct 2002. PubMed ID: 12239291. Show all entries for this paper.


Displaying record number 486

Download this epitope record as JSON.

HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location RT( LAI)
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Subtype B
Species (MHC/HLA) human(B*57:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords binding affinity, escape

Notes

References

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.

vanderBurg1997 S. H. van der Burg, M. R. Klein, O. Pontesilli, A. M. Holwerda, J. Drijfhout, W. M. Kast, F. Miedema, and C. J. M. Melief. HIV-1 Reverse Transcriptase-Specific CTL against Conserved Epitopes Do Not Protect against Progression to AIDS. J. Immunol., 159:3648-3654, 1997. PubMed ID: 9317165. Show all entries for this paper.


Displaying record number 63199

Download this epitope record as JSON.

HXB2 Location Pol(398-407)
RT(243-252)
DNA(3276..3305)
Pol Epitope Map
Author Location  
Epitope PIVLPEKDSW Epitope Alignment
PIVLPEKDSW epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA LNP-10: A*01:01, A*02:01, B*15:01, B*57:01, C*03:04, C*06:02
Country Canada
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells, protective allele

Notes

References

Elahi2020 Shokrollah Elahi, Shima Shahbaz, and Stan Houston. Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders Them to an Exhausted Phenotype in HIV-1 Infection. PLoS Pathog., 16(8):e1008696, Aug 2020. PubMed ID: 32760139. Show all entries for this paper.


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