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HIV Molecular Immunology Database

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Displaying record number 55274

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HXB2 Location HIV-2 proteins
DNA(3072..3098)
HIV-2 proteins Epitope Map
Author Location RT(329-337)
Epitope NPDVILIQY Epitope Alignment
Subtype HIV-2
Species (MHC/HLA) human(B35)
Immunogen HIV-1 or HIV-2 infection
Country Gambia
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS), HIV-2

Notes

References

RowlandJones1995 S. L. Rowland-Jones, J. Sutton, K. Ariyoshi, T. Dong, F. Gotch, S. McAdam, D. Whitby, S. Sabally, A. Gallimore, T. Corrah, M. Takiguchi, T. Schultz, A. McMichael, and H. Whittle. HIV-Specific Cytotoxic T Cells in HIV-Exposed but Uninfected Gambian Women. Nat. Med., 1:59-64, 1995. Four HIV-1 and -2 cross-reactive epitopes that are presented to CTL from HIV-infected Gambians by HLA-35 were identified. These peptides could elicit HIV-specific CTLs from 3 of 6 repeatedly exposed but seronegative sex workers who carry the HLA-B35 allele. Most CTL derived from HIV-2 positive donors also recognized the HIV-2 peptide and the analogous HIV-1 peptide. PubMed ID: 7584954. Show all entries for this paper.


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