Found 13 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(530-538) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9 | |
Species (MHC/HLA) | human(B*35:01, B*35:08) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(530-538) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | B*5801-IAW9 | |
Subtype | C | |
Species (MHC/HLA) | human(B*57, B*58:01) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | elite controllers and/or long-term non-progressors |
Koofhethile2016 Catherine K. Koofhethile, Zaza M. Ndhlovu, Christina Thobakgale-Tshabalala, Julia G. Prado, Nasreen Ismail, Zenele Mncube, Lungile Mkhize, Mary van der Stok, Nonhlanhla Yende, Bruce D. Walker, Philip J. R. Goulder, and Thumbi Ndung'u. CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. J. Virol., 90(15):6818-6831, 1 Aug 2016. PubMed ID: 27194762. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*57, B*58:01) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HLA cross-presentation, characterizing CD8+ T cells |
Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9, IAW9 RT | |
Subtype | C | |
Species (MHC/HLA) | human(B*57:02, B*57:03, B*58:01) | |
Immunogen | HIV-1 infection | |
Country | Botswana, South Africa, Zimbabwe | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding | |
Keywords | optimal epitope, HLA associated polymorphism, novel epitope |
Kloverpris2012 Henrik N. Kloverpris, Anette Stryhn, Mikkel Harndahl, Mary van der Stok, Rebecca P. Payne, Philippa C. Matthews, Fabian Chen, Lynn Riddell, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control. J. Virol., 86(2):919-929, Jan 2012. PubMed ID: 22090105. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*57:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, HLA cross-presentation, optimal epitope |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | RT(375-383) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*58) | |
Immunogen | HIV-1 infection | |
Country | Australia, Canada, Germany, United States | |
Experimental methods | ||
Keywords | escape, viral fitness and/or reversion, HLA associated polymorphism |
Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | RT(375-383) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*58:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*58:01) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, HLA cross-presentation, optimal epitope, HLA associated polymorphism |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(530-538) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9 | |
Species (MHC/HLA) | human(B*58:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | RT(375-383) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RT-IW9 | |
Subtype | C | |
Species (MHC/HLA) | human(B*58:01) | |
Immunogen | HIV-1 infection | |
Country | Botswana, South Africa, United Kingdom, Zimbabwe | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HLA associated polymorphism |
Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(530-538) | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | IW9 | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(530-538) RT(375-383) DNA(3672..3698) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IAMESIVIW
|
Epitope Alignment
|
Epitope Name | B58-IW9 | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | immunodominance, acute/early infection, chronic infection |
Streeck2009a Hendrik Streeck, Jonathan S. Jolin, Ying Qi, Bader Yassine-Diab, Randall C. Johnson, Douglas S. Kwon, Marylyn M. Addo, Chanson Brumme, Jean-Pierre Routy, Susan Little, Heiko K. Jessen, Anthony D. Kelleher, Frederick M. Hecht, Rafick-Pierre Sekaly, Eric S. Rosenberg, Bruce D. Walker, Mary Carrington, and Marcus Altfeld. Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells. J. Virol., 83(15):7641-7648, Aug 2009. PubMed ID: 19458000. Show all entries for this paper.
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