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HIV Molecular Immunology Database

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Displaying record number 919

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MAb ID 3G12
HXB2 Location Nef(51-71)
DNA(8947..9009)
Nef Epitope Map
Author Location Nef(51-71 BRU)
Epitope TNAACAWLEAQEEEEVGFPVT Epitope Alignment
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgG2a)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade BRU
Vaccine component Nef

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Ovod1992 V. Ovod, A. Lagerstedt, A. Ranki, F. O. Gombert, R. Spohn, M. Tahtinen, G. Jung, and K. J. Krohn. Immunological Variation and Immunohistochemical Localization of HIV-1 Nef Demonstrated with Monoclonal Antibodies. AIDS, 6:25-34, 1992. Ten anti-Nef MAbs were generated and mapped. Nef is expressed in two isomorphic forms, and was shown to be expressed mainly in the Golgi complex and at the nuclear membrane, but occasionally x in the nucleus, particularly in MT-4 cells. PubMed ID: 1371924. Show all entries for this paper.


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