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HIV Molecular Immunology Database

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Found 8 matching records:

Displaying record number 190

Download this epitope record as JSON.

MAb ID 1C4
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Haugan1995 I. R. Haugan, B. M. Nilsen, S. Worland, L. Olsen, and D. E. Helland. Characterization of the DNA-Binding Activity of HIV-1 Integrase Using a Filter Binding Assay. Biochem. Biophys. Res. Commun., 217:802-810, 1995. PubMed ID: 8554601. Show all entries for this paper.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 191

Download this epitope record as JSON.

MAb ID 2C11
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 192

Download this epitope record as JSON.

MAb ID 2E3
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.

Ovod1992 V. Ovod, A. Lagerstedt, A. Ranki, F. O. Gombert, R. Spohn, M. Tahtinen, G. Jung, and K. J. Krohn. Immunological Variation and Immunohistochemical Localization of HIV-1 Nef Demonstrated with Monoclonal Antibodies. AIDS, 6:25-34, 1992. Ten anti-Nef MAbs were generated and mapped. Nef is expressed in two isomorphic forms, and was shown to be expressed mainly in the Golgi complex and at the nuclear membrane, but occasionally x in the nucleus, particularly in MT-4 cells. PubMed ID: 1371924. Show all entries for this paper.


Displaying record number 194

Download this epitope record as JSON.

MAb ID 3F9
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 2 of 2 notes.

References

Showing 1 of 1 references.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 195

Download this epitope record as JSON.

MAb ID 5F8
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Haugan1995 I. R. Haugan, B. M. Nilsen, S. Worland, L. Olsen, and D. E. Helland. Characterization of the DNA-Binding Activity of HIV-1 Integrase Using a Filter Binding Assay. Biochem. Biophys. Res. Commun., 217:802-810, 1995. PubMed ID: 8554601. Show all entries for this paper.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 196

Download this epitope record as JSON.

MAb ID 6G5
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 197

Download this epitope record as JSON.

MAb ID 7B6
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


Displaying record number 198

Download this epitope record as JSON.

MAb ID 7C6
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


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