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MAb ID | B242 | |
---|---|---|
HXB2 Location | Env(83-92) DNA(6471..6500) |
Env Epitope Map |
Author Location | gp120(83-92 LAI) | |
Epitope |
EVVLVNVTEN
|
Epitope Alignment
|
Subtype | B | |
Ab Type | gp120 C1 | |
Neutralizing | ||
Species (Isotype) | mouse(IgG1) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | protein |
---|---|
Vaccine strain | B clade NL43 |
Vaccine component | gp160 |
Showing 1 of 1 note.
Showing 1 of 1 reference.
Bristow1994 R. G. W. Bristow, A. R. Douglas, J. J. Skehel, and R. S Daniels. Analysis of murine antibody responses to baculovirus-expressed human immunodeficiency virus type 1 envelope glycoproteins. J. Gen. Virol., 75:2089-2095, 1994. BALB/c mice were immunized with baculovirus expressed gp160 or gp120, and 15 MAbs were generated. No MAbs generated in this study neutralized reference strains, using a tetrazolium-based cytotoxicity assay to test for neutralization. Ten of the Mabs were mapped by peptide ELISA, and seven reacted with the C1 region, one with V2, one with V4, and one with the C-terminal end. PubMed ID: 7519249. Show all entries for this paper.
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