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MAb ID | 12G-A8g2 | |
---|---|---|
HXB2 Location | Gag(86-115) DNA(1045..1134) |
Gag Epitope Map |
Author Location | p17(86-115) | |
Epitope |
YCVHQRIEIKDTKEALDKIEEEQNKSKKKA
|
Epitope Alignment |
Ab Type | ||
Neutralizing | ||
Species (Isotype) | rat(IgG2a) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | HIV infected-cell lysate |
---|---|
Vaccine strain | B clade IIIB |
Vaccine component | HIV-1 |
Showing 2 of 2 notes.
Showing 2 of 2 references.
Maksiutov2002 A. Z. Maksiutov, A. G. Bachinskii, and S. I. Bazhan. [Searching for Local Similarities Between HIV-1 and Human Proteins. Application to Vaccines]. Mol Biol (Mosk), 36(3):447-459, May-Jun 2002. Article in Russian. PubMed ID: 12068630. Show all entries for this paper.
Shang1991 F. Shang, H. Huang, K. Revesz, H.-C. Chen, R. Herz, and A. Pinter. Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells. J. Virol., 65:4798-4804, 1991. Six MAbs with linear epitopes were mapped. These Abs could only bind to HIV-infected cells that had been permeablized with acetone. Only G11g1 and G11h3, two antibodies that did not bind to peptides, but only to intact p17, could react with live HIV-1 infected cells. These antibodies were not neutralizing. PubMed ID: 1714518. Show all entries for this paper.
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