Found 1 matching record:
Download this epitope record as JSON.
MAb ID | IIIB-V3-01 | |
---|---|---|
HXB2 Location | Env(320-328) DNA(7182..7208) |
Env Epitope Map |
Author Location | gp120( IIIB) | |
Research Contact | Jon Laman | |
Epitope |
IGKIGNMRQ
|
Epitope Alignment
|
Ab Type | gp120 V3 // V3 glycan (V3g) | |
Neutralizing | ||
Species (Isotype) | mouse(IgG1) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | peptide |
---|---|
Vaccine strain | B clade IIIB |
Vaccine component | Env V3 |
Showing 4 of 4 notes.
Showing 2 of 2 references.
Laman1993 J. D. Laman, M. M. Schellekens, G. K. Lewis, J. P. Moore, T. J. Matthews, J. P. M. Langedijk, R. H. Meloen, W. J. A. Boersma, and E. Claassen. A Hidden Region in the Third Variable Domain of HIV-1 IIIB gp120 Identified by a Monoclonal Antibody. AIDS Res. Hum. Retroviruses, 9:605-612, 1993. A peptide (FVTIGKIGNMRQAHC) induced MAb binds to the carboxy-terminal flank of the V3-loop, but the epitope is only exposed on gp120 when it is treated with SDS-DTT. PubMed ID: 8369165. Show all entries for this paper.
Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.
This is a legacy search page. It is deprecated, will receive no more updates, and will eventually be removed. Please use the new search pages.