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MAb ID | CD-4/1 (CB-4/1/1/F6) | |
---|---|---|
HXB2 Location | Gag(178-188) DNA(1321..1353) |
Gag Epitope Map |
Author Location | p24(182-197) | |
Epitope |
GATPQDLNTML
|
Epitope Alignment
|
Ab Type | ||
Neutralizing | ||
Species (Isotype) | mouse(IgG2aκ) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | beta-galactosidase fusion protein |
---|---|
Vaccine component | p24 Gag |
Showing 4 of 4 notes.
Showing 5 of 5 references.
Grunow1990 R. Grunow, R. Giess, T. Portsman, H. Dopel, K. Hansel, and R. von Baehr. Development and Biological Testing of Human and Murine Antibodies against HIV Antigens. Z. Klin. Med., 45:367-369, 1990. Show all entries for this paper.
Franke1992 L. Franke, R. Grunow, R. Meissner, T. Portsman, and R. von Baehr. Inhibition of HIV-1 Infection In Vitro by Murine Monoclonal Anti-p24 Antibodies. J. Med. Virol., 37:137-142, 1992. PubMed ID: 1629712. Show all entries for this paper.
Hohne1993 W. E. Hohne, G. Kuttner, S. Kiessig, G. Housdorf, R. Grunow, K. Winkler, H. Wessner, E. Giessmann, R. Stieger, J. Schneider-Mergener, R. von Baehr, and D. Schomburg. Structural Base of the Interaction of a Monoclonal Antibody against p24 of HIV-1 with Its Peptide Epitope. Mol. Immunol., 30:1213-1221, 1993. PubMed ID: 7692237. Show all entries for this paper.
Glaser1996 R. W. Glaser and G. Hausdorf. Binding Kinetics of an Antibody against HIV p24 Core Protein Measured with Real-Time Biomolecular Interaction Analysis Suggest a Slow Conformational Change in Antigen p24. J. Immunol. Methods, 189:1-14, 1996. The MAb CD-4/1 and p24 have unusual biphasic kinetics of association. PubMed ID: 8576571. Show all entries for this paper.
Ehrhard1996 B. Ehrhard, R. Misselwitz, K. Welfle, G. Hausdorf, R. W. Glaser, J. Schneider-Mergener, and H. Welfle. Chemical Modification of Recombinant HIV-1 Capsid Protein p24 Leads to the Release of a Hidden Epitope Prior to Changes of the Overall Folding of the Protein. Biochemistry, 35:9097-9105, 1996. PubMed ID: 8703914. Show all entries for this paper.
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