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MAb ID | JM4-IgG2b | |
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HXB2 Location | Env | Env Epitope Map |
Author Location | ||
Epitope |
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Ab Type | gp120 CD4bs, gp120 CD4i | |
Neutralizing | P (tier 2) View neutralization details | |
Species (Isotype) | llama(IgG2b) | |
Patient | ||
Immunogen | vaccine | |
Keywords | antibody binding site, antibody generation, broad neutralizer, structure |
Vaccine type | recombinant protein |
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Vaccine component | gp140 |
Adjuvant | Incomplete Freund's Adjuvant (IFA) |
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Showing 1 of 1 reference.
Isolation Paper
Acharya2013
Priyamvada Acharya, Timothy S. Luongo, Ivelin S. Georgiev, Julie Matz, Stephen D. Schmidt, Mark K. Louder, Pascal Kessler, Yongping Yang, Krisha McKee, Sijy O'Dell, Lei Chen, Daniel Baty, Patrick Chames, Loic Martin, John R. Mascola, and Peter D. Kwong. Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites. J. Virol., 87(18):10173-10181, Sep 2013. PubMed ID: 23843638.
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