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MAb ID | 2C11 | |
---|---|---|
HXB2 Location | Pol(716-731) DNA(4230..4277) |
Pol Epitope Map |
Author Location | Integrase(1-16 HXB2) | |
Epitope |
FLDGIDKAQDEHEKYH
|
Epitope Alignment
|
Subtype | B | |
Ab Type | N-term | |
Neutralizing | ||
Species (Isotype) | mouse(IgG1κ) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | protein |
---|---|
Vaccine strain | B clade HXB2 |
Vaccine component | Int |
Showing 1 of 1 note.
Showing 1 of 1 reference.
Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.
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