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LOCUS HIV1U35971 656 bp DNA linear VRL 04-FEB-1997
DEFINITION Human immunodeficiency virus type 1 sample P2.31-8, envelope
glycoprotein (env) gene, C2-V5, partial cds
ACCESSION U35971
VERSION U35971.1 GI:1144760
KEYWORDS .
SOURCE Human immunodeficiency virus 1 (HIV-1)
ORGANISM Human immunodeficiency virus 1 Viruses; Retro-transcribing viruses;
Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus
group
REFERENCE 1 (bases 1 to 656)
Show all sequences for reference 1
AUTHORS Wolinsky,S.M., Korber,B.T., Neumann,A.U., Daniels,M.,
Kunstman,K.J., Whetsell,A.J., Furtado,M.R., Cao,Y., Ho,D.D.,
Safrit,J.T. and Koup,R.A.
TITLE Adaptive evolution of human immunodeficiency virus-type 1 during
the natural course of infection
JOURNAL Science 272 (5261), 537-542 (1996)
PUBMED 8614801
REFERENCE 2 (bases 1 to 656)
Show all sequences for reference 2
AUTHORS McDonald,D.
TITLE Direct Submission
JOURNAL Submitted (12-SEP-1995) D. McDonald, Theoretical Biology, T-10, Los
Alamos National Lab, Los Alamos, NM 87545, USA
REFERENCE 3
Show all sequences for reference 3
AUTHORS Kils-Hutten,L., Cheynier,R., Wain-Hobson,S. and Meyerhans,A.
TITLE Phylogenetic reconstruction of intrapatient evolution of human
immunodeficiency virus type 1: predominance of drift and purifying
selection.
JOURNAL J Gen Virol. 2001 Jul;82(Pt 7):1621-7.
PUBMED 11413373
COMMENT Sequence related to longitudinal study of HIV genetic variation and
its relation to rate of disease progression. These patients are
from the Chicago MACS cohort. In the study, P1 & P2 were rapid
progressors, P3 & P4 normal progressors, and P5 & P6
non-progressors. Their estimated years of seroconversion are as
follows: for P1, 1985, for P2, 1985, for P3, 1986, for P4, 1986,
for P5, 1984, and for P6, 1985. In the sample number, Px.y-z, x
stands for the patient number, y is the number of months after the
estimated date of seroconversion, and z is the clone number. This
patient, P2, is a rapid progressor. P2 sequences available are
(dates after seroconversion indicated): 3 months (6 clones), 9
months (6 clones), 15 months (7 clones), 18 months (7 clones), 21
months (7 clones), 27 months (7 clones), 31 months (5 clones).
FEATURES Location/Qualifiers
source 1..656
/organism="Human immunodeficiency virus 1"
/proviral="Human immunodeficiency virus 1"
/mol_type="genomic DNA"
/isolate="sample P2.31-8"
/db_xref="taxon:11676"
/note="PCR amplified proviral DNA from peripheral blood
mononuclear cells"
gene 1..656
/gene="env"
CDS <1..>656
/gene="env"
/note="C2-V5"
/codon_start="3"
/transl_table="1"
/product="envelope glycoprotein"
/protein_id="AAB41933.1"
/db_xref="GI:1144761"
/translation="GSLAXEEIIIRSENFTNNAKTIIVQLNEPVEINCTRPNNNTRKG
IHVGPGRAFYTTGDIIGNIRQAHCNISKAKWDNTLKQIVTKLREQFGNKTIVFNQSSG
GDPEIVMHSFNCGGEFFYCNSTQLFNSTWNNTDGSNNTEGNITLPCRIKQIINLWQEV
GKAMYAPPIRGQIRCSSNITGLLLTRDGGSNEDNNMTEIFRPGGGDMRDNWRSELYKY
"
BASE COUNT 268 a 101 c 136 g 150 t 1 other
ORIGIN
1 atggcagtct agcagnagaa gagataataa ttagatctga aaacttcacg aacaatgcaa
61 aaaccataat agtacagctg aatgaacctg tagaaattaa ttgtacaaga cccaacaaca
121 atacaagaaa aggtatacat gtaggaccag ggagagcatt ctatacaaca ggagatataa
181 taggaaacat aagacaagca cattgtaaca ttagtaaggc caaatgggat aacactttaa
241 aacagatagt tacaaaatta agagaacaat ttgggaataa aacaatagtc tttaaccaat
301 cctcaggagg ggacccagaa attgtaatgc acagttttaa ttgtggaggg gaatttttct
361 actgtaattc aacacaactg tttaatagta cttggaataa tactgacggg tcaaataaca
421 ctgaaggaaa tatcacactc ccatgtagaa taaaacaaat tataaacctg tggcaggaag
481 taggaaaagc aatgtatgcc cctcccatca gaggacaaat tagatgttca tcaaatatta
541 cagggttgct attaacaaga gatggtggta gtaacgagga caacaacatg accgagatct
601 tcagacctgg gggaggagat atgagggaca attggagaag tgaattgtat aaatat
//
last modified: Tue May 31 10:56 2022